Research advance in autosomal recessive polycystic kidney disease
- VernacularTitle:常染色体隐性遗传性多囊肾病的研究进展
- Author:
Lina SUN
;
Lin ZHANG
;
Qinghong LIANG
- Publication Type:Journal Article
- Keywords:
polycystic kidney;
autosomal recessive;
gene;
mutation;
congenital hepatic ifbrosis
- From:
Journal of Clinical Pediatrics
2015;(3):295-298
- CountryChina
- Language:Chinese
-
Abstract:
Autosomal recessive polycystic kidney disease (ARPKD) had a low incidence, and mainly in neonates or infants. It is caused by mutations of the polycystic kidney and hepatic disease 1 gene (PKHD1). The pathogenesis of ARPKD is still not clear. The principal of treatment is focused on the control of complications and slow down the progression. In this article, the research advances in the pathogenesis and treatment of ARPKD was reviewed.
