Study progresses in respiratory mucosal immunity and related diseases
10.3969/j.issn.1000-484X.2015.03.001
- VernacularTitle:呼吸道黏膜免疫及其相关疾病研究进展
- Author:
Jian WANG
;
Zhigang TIAN
- Publication Type:Journal Article
- Keywords:
Respiratory tract;
Mucosal immunity;
Respiratory disease;
Commensal bacteria;
Common mucosal immune system
- From:
Chinese Journal of Immunology
2015;(3):289-294
- CountryChina
- Language:Chinese
-
Abstract:
As the passage of environmental atmosphere entering the body,the respiratory tract suffers persistent challenge from foreign substances.The mucosal immune system of the respiratory tract is the main defense line against the invasion of pathogens,which needs to distinguish not only beneficial and detrimental materials but also resident and pathogenic bacteria.Because the knowledge about respiratory mucosal immunity is limited,the immunopathologic mechanisms of related diseases such as asthma,acute lung injury, chronic obstructive pulmonary disease, and respiratory infection need investigation.The study about the immune features of the respiratory tract not only contributes to the prevention and treatment of respiratory disease but also provides ideas for the development and design of new vaccines and medicines.