Obesity and insulin resistance in apparently healthy Korean men.
- Author:
Seung Ha PARK
1
;
Won Young LEE
;
Yong Su LEE
;
Eun Jung RHEE
;
Sun Woo KIM
Author Information
1. Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. drlwy@samsung.co.kr
- Publication Type:Original Article
- Keywords:
Obesity;
Insulin resistance;
Coronary heart disease
- MeSH:
Apolipoprotein A-I;
Apolipoproteins;
Apolipoproteins B;
Asian Continental Ancestry Group;
Blood Glucose;
Blood Pressure;
Body Mass Index;
C-Reactive Protein;
Cholesterol;
Cholesterol, HDL;
Cholesterol, LDL;
Coronary Disease;
Cross-Sectional Studies;
Fasting;
Homeostasis;
Humans;
Insulin Resistance*;
Insulin*;
Male;
Multiple Endocrine Neoplasia Type 1;
Obesity*;
Overweight;
Prevalence;
Risk Factors;
Triglycerides;
Waist Circumference
- From:Korean Journal of Medicine
2003;65(4):451-457
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Several reports document Asians have a strong tendency of developing insulin resistance. We aimed to evaluate the relative effects of insulin resistance and obesity on coronary heart disease (CHD) risk factors and to clarify whether insulin resistance accentuates the effect of obesity on CHD risk factors in apparently healthy men. METHODS: We conducted the cross-sectional survey of 4,067 apparently healthy Korean men aged 20-83 years, with a body mass index (BMI) ranging from 15.19 to 40.29 kgm-2. Insulin resistance was defined as the highest decile of homeostasis model assessment (HOMA-IR) in the lean group (BMI<23 kgm-2; 1,438 subjects). RESULTS: The prevalence of insulin resistance was 24.7% in the overweight subgroup (23
