Primary cytotoxic T-cell lymphoma of uterine cervix: A case report.
- Author:
Ji Hye KIM
1
;
Jae Yong KWAK
;
Chang Yeol YIM
Author Information
1. Department of Internal Medicine, Chonbuk National University Medical School, Chonju, Korea. jykwak@moak.chonbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Uterine cervix;
Lymphoma;
T-cell
- MeSH:
Biopsy;
Cervix Uteri*;
Cyclophosphamide;
Doxorubicin;
Drug Therapy;
Female;
Gynecological Examination;
Humans;
Lymphoma;
Lymphoma, B-Cell;
Lymphoma, Non-Hodgkin;
Lymphoma, T-Cell*;
Middle Aged;
T-Lymphocytes*;
Vincristine
- From:Korean Journal of Medicine
2003;65(4):486-490
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Non-Hodgkin's lymphoma can involve the gynecologic tract, most often as a manifestation of systemic involvement. Primary lymphomas of the female genital tract are rare. Most involve the cervix rather than the uterine corpus. All of those previously reported have been B-cell lymphomas, with the exception of several case reports. Primary T-cell lymphoma of the uterine cervix is rare. We describe a rare case of primary cytotoxic T-cell lymphoma of the uterine cervix, Ann Arbor stage IE in a 55-year-old woman. The tumor, incidentally disclosed at gynecological examination, appeared as diffuse cervical enlargement with mucosal erosion. A biopsy was taken and showed diffuse infiltration of variable sized lymphoma cells. Neoplastic cells were positive for LCA, CD3, TIA-1 and consistent with cytotoxic T-cell lymphoma. She was treated with 3 cycles of cyclophosphamide, doxorubicin, vincristine, and prednisolone(CHOP). After chemotherapy, the patient was treated by pelvic external radiation therapy. At present, the patient is well and disease-free.
