The Effectiveness of Intratympanic Steroid Therapy and Systemic Steroid Therapy on the treatment of Idiopathic Sudden Sensorineural Hearing Loss Patients with Damaged Glucose Tolerance
10.3969/j.issn.1006-7299.2015.02.010
- VernacularTitle:鼓室内与静脉注射糖皮质激素治疗伴糖耐量异常突发性聋疗效比较
- Author:
Zhiping TANG
;
Xiangping WU
;
Ruoqing QIU
;
Qingli CHEN
;
Zhisheng LIANG
;
Yindi LIANG
;
Shuting TIAN
- Publication Type:Journal Article
- Keywords:
Intratympanic steroid therapy;
Idiopathic sudden sensorineural hearing loss;
Damaged glu-cose tolerance
- From:
Journal of Audiology and Speech Pathology
2015;(2):160-162
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of intratympanic steroid therapy compared with systemic ster‐oid therapy on the treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) patients with damaged glu‐cose tolerance .Methods Fifty first -diagnosed unilateral ISSNHL patients with damaged glucose tolerance were randomized devided equally to the intervention group (intratympanic steroid therapy) or the control group (systemic steroid therapy) ,all patients received conventional drug therapy simultaneously .Pure-tone hearing threshold tests were performed in all patients every 3 days after the first time ,and repeated measures anova was used to assess effects of hearing recovery accompanied with time .Results The mean hearing threshold in the control group de‐creased from 85 .4 ± 5 .6 dB to 48 .2 ± 4 .9 dB ,while in the intervention group it decreased from 84 .8 ± 5 .6 dB to 31 .7 ± 4 .6 dB .Total effective rate in the intervention group (84 .00% ,21/95) was higher than that in the control group (68 .00% ,17/25)(P<0 .05) .Conclusion The intratympanic steroid therapy is more effective than systemic steroid therapy in the treatment of ISSNHL patients with damaged glucose tolerance .
