Comparison between cytopathologic and histopathologic diagnoses in CT-guided percutaneous lung biopsy specimens
10.13315/j.cnki.cjcep.2015.02.016
- VernacularTitle:肺穿刺活检标本细胞学与组织学检查的比较分析
- Author:
Rong RONG
;
Yan WU
;
Qing YAO
;
Yunsong WU
;
Zhihong ZHANG
- Publication Type:Journal Article
- Keywords:
lung neoplasms;
CT-guided;
percutaneous lung biopsy;
cytology examination
- From:
Chinese Journal of Clinical and Experimental Pathology
2015;(2):181-183
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To study the cytopathologic features of CT-guided percutaneous lung biopsy samples and to evaluate the role of cytopathology in the diagnosis and staging of lung carcinomas, as compared to histopathology. Methods Four-hundred twenty-five specimens were collected by CT-guided percutaneous lung biopsy which were also confirmed by histological diagnosis. Direct smears were performed for each case. Cytological and histological examination was carried out. Results The sensitivity, specificity, false positive rate, false negative rate and accuracy of cytopathology in diagnosing lung carcinomas by CT-guided percutaneous lung biopsy was 86. 6% (264/305), 100% (120/120), 0 (0/120), 13. 4% (41/305), 90. 4% (384/425), respectively. Overall 51. 1%(135/264) of the cases were precisely typed, including 77. 6% (83/107) of adenocarcinoma, 76. 9% (40/52) of squamous cell car-cinoma and 75. 0% (9/12) of small cell carcinoma. Conclusions Cytopathology of CT-guided percutaneous lung biopsy specimens is sensitive and accurate for diagnosing pulmonary carcinomas. In some cases, the lung carcinoma can be precisely typed. Therefore, it is useful for diagnosing and staging lung carcinomas.
