Anti-inflammatory effect of triterpenoids from Antrodia camphorat a
10.3969/j.issn.1000-4718.2015.02.032
- VernacularTitle:樟芝三萜类化合物的抗炎作用
- Author:
Yihong ZHANG
;
Zongjie ZHAO
;
Haitao XIE
;
Xiangyang ZHANG
;
Yu SONG
- Publication Type:Journal Article
- Keywords:
Antrodia camphorata;
Triterpenoids;
Inflammation
- From:
Chinese Journal of Pathophysiology
2015;(2):369-373
- CountryChina
- Language:Chinese
-
Abstract:
The morbidity of inflammation-associated tumor is high .Prevention and treatment of inflammation play a positive role in delaying the occurrence and development of cancer .Antrodia camphorata, an endemic fungus in Tai-wan, possesses significant anti-inflammatory effect.So far, 35 anti-inflammatory active components from Antrodia camphorata have been identified , among which triterpenoids account for the most .Studies have revealed that triterpenoids , including ergostanes and lanostanes , have significant anti-inflammatory activities .Because of their structures , especially those of the ergostanes , are similar to the structures of cholesterol and steroid hormones , their anti-inflammatory mechanism may be related to mimic the steroid hormones or interfere with the effect of cholesterol .
