Analysis of serum levels of CA125 and SCC-Ag in patients with different gynecological diseases
10.3969/j.issn.1673-4130.2014.21.014
- VernacularTitle:不同妇科疾病患者血清CA125和SCC-Ag水平分析
- Author:
Ping LI
;
Zhibin ZHANG
- Publication Type:Journal Article
- Keywords:
carbohydrate antigen 125;
squamous cell carcinoma antigen;
gynecological diseases
- From:
International Journal of Laboratory Medicine
2014;(21):2895-2896
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the serum levels of carbohydrate antigen 125(CA125)and squamous cell carcinoma antigen (SCC-Ag)in patients with different gynecological diseases ,and to investigate the clinical significance of serum CA125 and SCC-Ag in the diagnosis of gynecological diseases .Methods The levels of CA125 and SCC-Ag in serum were detected by chemiluminescence method in 272 hospitalized patients of gynecological and 20 health examination women(normal control group) .Results The serum level and the positive rate of CA125 were increased in different disease groups ,which were significantly increased in endometriosis , adenomyosis ,and cervical cancer groups and were significantly different from the normal control group(P<0 .01) .The serum level and positive rate of SCC-Ag in cervical cancer group were significantly higher than normal control group(P<0 .01) .Conclusion Serum CA125 can be used as an indicator of gynecological disease screening ,and serum SCC-Ag is a specific tumor marker of cervi-cal cancer .
