Comparative analysis of various clinical laboratory diagnosis methods of pulmonary tuberculosis
10.3969/j.issn.1673-4130.2014.21.034
- VernacularTitle:多种肺结核临床实验室诊断方法的比较分析
- Author:
Qiang ZHENG
;
Chaojin LI
;
Li GOU
;
Peng HE
;
Xiaoyuan XU
- Publication Type:Journal Article
- Keywords:
tuberculosis;
sputum smear;
sputum culture
- From:
International Journal of Laboratory Medicine
2014;(21):2941-2942
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the value of combination of various clinical laboratory methods in the diagnosis of Mycobacteri-um tuberculosis(MTB) .Methods T-SPOT .TB ,sputum smear ,sputum culture ,and MTB-DNA detection were used to detect MTB .The sensitivity ,specificity ,rate of missed diagnosis ,coincidence rate and correct diagnosis index for tuberculosis diagnosis of the four methods and their pairwise combinations were analyzed and compared .Results Comparing with other methods ,T-SPOT . TB combined with MTB-DNA detection had the highest sensitivity ,coincidence rate and correct diagnosis index ,and the lowest rate of missed diagnosis ,with significant difference(P<0 .05) .Conclusion T-SPOT .TB combined with MTB-DNA detection could be used as an adjuvant method for the early diagnosis of tuberculosis .
