Attention to the antibiotic resistance caused by bacterial biofilm and its solutions
- VernacularTitle:重视细菌生物被膜导致的细菌耐药及其解决方案
- Author:
Yong WU
;
Lihua CHEN
- Publication Type:Journal Article
- Keywords:
Bacteria;
Biofilms;
Drug resistance,bacterial;
Clinical protocols
- From:
Chinese Journal of Laboratory Medicine
2014;(10):725-727
- CountryChina
- Language:Chinese
-
Abstract:
Biofilm formation makes bacteria adopt a multicellular lifestyle.Compared to planktonic cells, biofilm-grown cells express an increased resistance to antimicrobial agents.Bacterial biofilm formation is a crucial step in the pathogenesis of many subacute and chronic bacterial infections.In clinical setting, biofilm can cause bacterial biofilm disease and biomaterial associated infection.Understanding the mechanisms involved in biofilm-associated antimicrobial resistance is key to the development of new solutions.