Advance in research on pharmacogenomics of vitamin
10.3969/j.issn.1001-1978.2014.11.005
- VernacularTitle:维生素的药物基因组学研究进展
- Author:
Yueli ZHANG
;
Honghao ZHOU
;
Wei ZHANG
- Publication Type:Journal Article
- Keywords:
vitamin;
deficiency;
individualization;
drug reac-tion;
pharmacogenomics;
single nucleotide polymorphisms
- From:
Chinese Pharmacological Bulletin
2014;(11):1503-1507
- CountryChina
- Language:Chinese
-
Abstract:
Vitamin is necessary and important for humans and an-imals to maintain normal physiological function, metabolism, and growth. The studies suggest that vitamin is one of the factors which play a role in the activity of enzymes, and it is coenzyme of many enzyme or an important component of coenzyme. The lack of vitamins causes a metabolic vitamin deficiency. Pharma-cogenomics research the relationship between human genetic vari-ation and drug reaction, using the information to solve the differ-ent reactions among the different individuals of the same drug. Vitamins, which constitute human tissues and maintain normal physiological functions, are also an important part for the phar-macogenomics study.