Analgesic effect evaluation of dezocine in postoperative analgesia in abdominal surgery
- VernacularTitle:地佐辛用于腹部全麻手术后的镇痛效果评价
- Author:
Nan LI
;
Pingying WANG
- Publication Type:Journal Article
- Keywords:
dezocine;
fentanyl;
postoperative analgesia;
abdominal surgery
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;37(7):156-157
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate analgesia of dezocine in abdominal anesthesia postoperative.Methods 80 cases (ASA I ~II)abdominal surgery under general anesthesia patients required postoperative analgesia,according to different postoperative analgesia drug,patients were randomly divided into 2 groups:dezocine group (group D),dezocine 0.6 mg/kg+ondansetron 4mg plus 0.9% sodium chloride to 100 mL,loading dose of intravenous patient controlled analgesia (PCIA);fentanyl group (group F),fentanyl 12 g/kg+ondansetron 4mg plus 0.9% sodium chloride to 100 mL,loading dose plus PCIA,recorded after 2,4,8,12,24,48 h visual analog scale (VAS)and Ramsay sedation score.Results The 2 groups were not statistically significant differences in VAS score and Ramsay score,and the incidence of adverse reaction of fentanyl group was significantly higher than that of dezocine group (P<0.01).Conclusion Dezocine group could provide analgesia safe and comfortable for patients after abdominal operation under general anesthesia.
