Vasculogenic mimicry in cancer
10.3760/cma.j.issn.1673-422X.2014.11.008
- VernacularTitle:血管生成拟态在恶性肿瘤的研究进展
- Author:
Pisong LI
;
Jianyi LI
;
Wenhai ZHANG
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Vascular endothelial growth factors;
Hypoxia inducible factor 1,alpha subunit;
MicroRNAs;
Vasculogenic mimicry
- From:
Journal of International Oncology
2014;41(11):824-827
- CountryChina
- Language:Chinese
-
Abstract:
Vasculogenic mimicry (VM) is one of the blood supply patterns in malignant tumor,and the molecular mechanism of breast malignant tumor VM is complicated.The plasticity of tumor cells and variety of molecules regulation play important roles in the mechanism of VM.At the same time,the hypoxic microenvironment and microRNA (miRNA) are associated with the occurrence and development of VM,especially in breast malignant tumor,and they are expected to become important diagnostic and prognostic indicators in breast cancer.
