Clinical significance of determination of serum thyroid hormone in patient with type 2 diabetes mellitus
10.3969/j.issn.1673-4130.2014.20.020
- VernacularTitle:2型糖尿病患者血清甲状腺激素检测的临床意义
- Author:
Zhihong MA
;
Hongyu WU
;
Liguo ZHU
;
Yuesong LI
- Publication Type:Journal Article
- Keywords:
diabetes mellitus;
thyroid hormone;
clinical significance
- From:
International Journal of Laboratory Medicine
2014;(20):2767-2768
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the change of serum thyroid hormone related indicators and the probability of occurrence of thyroid dysfunction abnormality in the patient with type 2 diabetes mellitus(T2DM).Methods 86 patients with T2DM and 61 age-matched and gender-matched individuals with healthy physical examination as controls were selected and detected serum FT3,FT4 and TSH by the electrochemiluminescence method Results The serum FT3,FT4 and TSH in the T2DM group were 5.09 pmol/L, 17.32 pmol/L and 2.81 mIU/L respectively;which in the normal control group were 4.99 pmol/L,17.24 pmol/L and 2.71 mIU/L respectively,the differences between the two groups had no statistical significance(P >0.05).Among 86 cases of T2DM,29 cases had the serum abnormal TSH with the abnormal rate of 33.7%,which in the control group was 14.8% with statistical difference between the two groups(P <0.05).Among T2DM patients,the TSH abnormal rate of in females was 42.1%,which was higher than 17.2% in males.Conclusion The serum thyroid hormone detection is necessary for the T2DM patients,especially female pa-tients,which is conducive to early screening,prevention and treatment.