Study on serum autoantibody in patients with polycystic ovary syndrome in child-bearing period
10.3969/j.issn.1673-4130.2014.20.023
- VernacularTitle:育龄期多囊卵巢综合征患者血清自身抗体研究
- Author:
Yueyun XIANG
;
Anhua MAO
;
Hao TAN
- Publication Type:Journal Article
- Keywords:
polycystic ovary syndrome;
autoimmunity;
antibodies
- From:
International Journal of Laboratory Medicine
2014;(20):2773-2774
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between serum non-organ-specific autoantibodies and polycystic ovary syn-drome(PCOS).Methods A total of 69 patients with PCOS in child-bearing period treated in our hospital were selected as the study group and contemporaneous 69 healthy child-bearing year women were selected as the control group.Serum level of antinuclear anti-bodies (ANA)was measured by ELISA,serum level of anti-dsDNA was measured by colloidal gold spot infiltration assay and the extractable nuclear antigen (ENA)auto-antibodies profiles were measured by Western blot.Results Serum levels of ANA and an-ti-dsDNA antibodies in the study group were significantly elevated compared with the control group with statistical difference.Con-clusion Serum autoantibody positive exists in the patients with PCOS.
