Clinical value of detecting serum PTH and SF in patients with chronic kidney disease and their correlation with serum β2-MG
10.3969/j.issn.1673-4130.2014.20.010
- VernacularTitle:慢性肾脏病患者血清 PTH 和 SF 检测的临床价值与β2-MG 的相关性研究
- Author:
Zisheng LI
;
Wenyan QIN
;
Bo CHEN
;
Youqing SHE
- Publication Type:Journal Article
- Keywords:
chronic kidney disease;
serum ferritin;
parathormone;
β2-microglobulin
- From:
International Journal of Laboratory Medicine
2014;(20):2744-2745
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the change characteristics of serum ferritin(SF)and parathormone (PTH)levels in differ-ent stages of chronic kidney disease(CKD)and their correlation with serum beta 2-microglobulin(β2-MG).Methods The levels of serum PTH,SF andβ2-MG in different stages of CKD were detected and the detection results were compared with those in the con-trol group.The correlation between serum SF and PTH withβ2-MG in each stage of CKD was analyzed.Results The level of ser-um PTH,SF andβ2-MG in the compensation group had no statistical difference compared with the control group (P >0.05),while which had statistical differences among the decompensation group,renal failure group and uremia group (P <0.05)The correlation analysis showed that serum PTH was positively correlated with serumβ2-MG in 145 cases(r=0.92,P <0.05),and the serum SF level was also positively correlated with serumβ2-MG level(r=0.92,P <0.05).Conclusion Detecting serum PTH,SF andβ2-MG levels possesses the important clinical significance for understanding CKD condition and prognosis.
