Functions of platelets in tumor growth and metastasis
10.3760/cma.j.issn.1673-422X.2014.09.002
- VernacularTitle:血小板在肿瘤生长和转移中的作用
- Author:
Tianjia ZHANG
;
Suying DANG
- Publication Type:Journal Article
- Keywords:
Blood platelets;
Neoplasms;
Neoplasm metastasis
- From:
Journal of International Oncology
2014;(9):645-647
- CountryChina
- Language:Chinese
-
Abstract:
Increases of platelet amount and activation are associated with tumor metastasis.Current studies reveal that platelets participate in the process of tumor metastasis via promoting immune escape,adhe-sion and angiogenesis.The direct interactions between platelets and tumor cells are also founded as an important determinant in metastasis.The functions of platelets in tumor progression and metastasis suggest that platelets could be served as new potential targets for cancer treatment.