Applications and mechanism of some clinical common medications used as anti-cancer therapy sensitizer
10.3760/cma.j.issn.1673-422X.2014.09.004
- VernacularTitle:部分临床常用药物作为抗肿瘤增效药物的应用与机制
- Author:
Rutian LI
;
Xiaoping QIAN
;
Baorui LIU
- Publication Type:Journal Article
- Keywords:
Antineoplastic agents;
Proton pump inhibitors;
Sodium bicarbonate;
Hypoglycemic agents;
Cardiovascular agents
- From:
Journal of International Oncology
2014;(9):651-655
- CountryChina
- Language:Chinese
-
Abstract:
A number of medications have been proved to be able to either improve the antitumor effect of chemotherapeutics and molecular targeted drugs or reverse the resistance of tumors to chemotherapeutics and molecular targeted drugs,which are not traditionally used as anticancer drugs.Especially for late-stage tumors after multiple treatments,these agents are good alternatives when used independently or in combination with chemotherapeutics and molecular targeted drugs.These drugs include proton modulators,hypoglycemic agents and cardiovascular agents,etc.