Lower respiratory tract in patients with malignant tumor of fermentation bacteria infection of bacterial drug resistance analysis
10.3969/j.issn.1673-4130.2014.20.027
- VernacularTitle:恶性肿瘤患者非发酵菌下呼吸道感染的细菌耐药性分析
- Author:
Xuefeng LIAO
;
Mi LI
- Publication Type:Journal Article
- Keywords:
malignant tumors;
non-fermenting bacteria;
lower respiratory tract infections;
drug resistance
- From:
International Journal of Laboratory Medicine
2014;(20):2781-2783
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the drug resistance in cancer patients with secondary non-fermenting bacterial lower respir-atory tract infection in order to provide a basis for clinical rational use of antibacterial drugs.Methods The lower respiratory tract specimens were collected from the patients with malignant tumor and identified by the fully automated microbial identification sys-tem,the drug susceptibility test was performed by using K-B method and the drug susceptibility test results were judged according to CLSI 2012 standard.The data were analyzed by the WHONET 5.6 software.Results 172 strains of non-fermenting bacteria were isolated from the lower respiratory tract specimens in the patients with malignant tumors,in which Pseudomonas aeruginosa was maximum,accounted for 45.9%,followed by Acinetobacter baumannii and Stenotrophomonas maltophilia ,accounted for 36. 0% and 10.5 % respectively.The drug susceptibility test showed that five kinds of non-fermenter demonstrated the high resistance or multi-resistance to multiple antibacterial drugs.Conclusion Non-fermenting bacterial multi-drug resistant phenomenon is seri-ous,clinic should pay attention to non-fermenting bacterial infection and drug resistance monitoring,antibacterial drugs should be rationally used according to the drug susceptibility test results in order to reduce the generation of drug-resistant strains.
