Observation of homocysteine and blood uric acid in patients with type 2 diabetes mellitus complicating hypertension
10.3969/j.issn.1673-4130.2014.20.028
- VernacularTitle:2型糖尿病合并高血压患者同型半胱氨酸与血尿酸水平观察
- Author:
Duan CHEN
;
Hongliang WANG
- Publication Type:Journal Article
- Keywords:
type 2 diabetes mellitus;
hypertension;
homocysteine;
blood uric acid
- From:
International Journal of Laboratory Medicine
2014;(20):2784-2785
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between homocysteine(Hcy)and blood uric acid(UA)in the patients with type 2 diabetes mellitus(T2DM)complicating hypertension.Methods 85 patients with T2DM complicating hypertension were se-lected as the groupⅠ,78 patients with simple T2DM as the group Ⅱ and 74 individuals with healthy physical examination as the group Ⅲ.Hcy,UA,TC,TG and HDL-C were measured in all the subjects.Results Compared with group Ⅲ(control),the levels of Hcy,UA,TC and TG in the group Ⅰand groupⅡwere significantly increased(P <0.05),but the level of HDL-C was significantly decreased(P <0.05).Compared with the group Ⅱ(T2DM),the levels of Hcy,UA,TC and TG in the group Ⅰwere significantly in-creased(P <0.05 ),but the level of HDL-C was obviously decreased,the difference had statistical significance (P <0.05 ).There was good positive correlation between the Hcy level and the UA level in the patients with T2DM complicating hypertension (r =0.658,P <0.05).Conclusion The levels of Hcy and UA are significantly increased in the patients with T2DM especially complica-ting hypertension.High Hcy and high UA are the important risk factors of T2DM complicating cardiocerebrovascular diseases.
