Autoantibody detection analysis in abortion pregnant women in Shihezi
10.3969/j.issn.1673-4130.2014.20.031
- VernacularTitle:石河子流产孕妇自身抗体检测分析
- Author:
Ye ZHANG
- Publication Type:Journal Article
- Keywords:
abortion;
autoantibodies;
anti-cardiolipin antibodies
- From:
International Journal of Laboratory Medicine
2014;(20):2790-2791
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the autoantibody detection and abortion of pregnant women.Meth-ods The dot immunogold method,indirect immunofluorescence and enzyme-linked immunosorbent assay(ELISA)were used to de-tect serum anti-double stranded DNA antibody (dsDNA),anti-smooth muscle antibody (SMA),antinuclear antibody (ANA),anti-endometrial antibody (EMAb),anti-cardiolipin antibody(ACA),anti-sperm antibody (ASAb),anti-ovarian antibody(AoAb).Re-sults Compared with healthy pregnant women,the values of EMAb,ACA,AoAb,ANA and SMA in abortion pregnant women were increased with statistical differences (P <0.05).Conclusion EMAb,ACA,AoAb,ANA and SMA have high correlation with abortion of pregnant women.Confirming the causes of unexplained abortion and prenatal screening are especially important for the pregnant women in the border area.
