The study of low frequency fluctuation in the resting state between short-term heroin and methamphetamine abusers after withdrawal

VernacularTitle:短期吸食海洛因和冰毒者戒断后静息态低频振幅改变的研究
Author: Yang YU ; Mingwu LOU ; Lin LU ; Wenbin LIANG ; Yunxia SHEN
Publication Type:Journal Article
Keywords: heroin; methamphetamine; amplitude of low frequency fluctuation; resting-state functional MRI
From: Journal of Practical Radiology 2015;(6):887-890
CountryChina
Language:Chinese
Abstract: Objective To investigate the differences of low frequency fluctuation (ALFF)in the resting state between short-term heroin and methamphetamine abusers after withdrawal.Methods Sixteen male short-term heroin abusers and fourteen male short-term methamphetamine abusers were performed the functional magnetic resonance imaging (fMRI).The differences of ALFF be-tween the two groups were performed with preprocessing softwares.Threshold was set to 0.05.Results Compared with metham-phetamine-dependent patients,heroin-dependent patients showed increased ALFF in the left side of the lingual gyrus and the left ton-sil of cerebellum and decreased ALFF in the left side of the brain stem,midbrain and the left side of the cerebellar vermis.Conclusion There are differences between the short-term heroin and methamphetamine abusers in the function of the brain,mainly involving the brain regions associating with cognition and affection.