The study of distinguishing solid solitary pulmonary nodule with diffusion weighted imaging

VernacularTitle:磁共振 DWI 鉴别实性孤立性肺结节价值研究
Author: Jinjun REN ; Baohong ZHAO ; Xuerong ZI ; Yuhuan ZHANG ; Hongwei CHI ; Shuping WANG ; Qian XU ; Yanfang CHEN
Publication Type:Journal Article
Keywords: magnetic resonance imaging; diffusion weighted imaging; solitary pulmonary nodule
From: Journal of Practical Radiology 2015;(6):925-928
CountryChina
Language:Chinese
Abstract: Objective To evaluate the value of diffusion weighted imaging (DWI)in distinguishing the solid solitary pulmonary nodule (SPN).Methods 42 patients with SPN (malignant in 25 and benign in 1 7)who were confirmed by operation,biopsy or follow up after treatment underwent routine chest T1 WI,T2 WI and DWI.The b values were chosen as 300,500,800 and 1 000 s/mm2 ,and the corresponding apparent diffusion coefficient (ADC)values and the signal intensity (SI)were respectively measured.Results The ADC values and SI of benign and malignant SPNs were gradually reduced with increasing b value.The ADC value between benign and malignant SPNs was statistically significant with b value of 500 s/mm2 (P 500 =0.03 <0.05 ),meanwhile the SI was statistically significant with b values from 300 to 1000 s/mm2 (P 300 <0.001,P 500 =0.03 <0.05,P 800 =0.01 <0.05, P 1 000 =0.02<0.05).Conclusion Both SI and ADC value of DWI play important role in distinguishing benign and malignant SPNs, and the diagnostic efficiency of SI is superior to ADC value.