Molecular marker miRNA for the diagnosis, treatment and prognosis of lung cancer
10.3969/j.issn.1000-8179.20140754
- VernacularTitle:肺癌诊治和预后判断分子标志物miRNA
- Author:
Cong JI
;
Changyuan YU
;
Zhihua CHEN
- Publication Type:Journal Article
- Keywords:
lung cancer;
miRNA;
diagnosis;
prognosis;
treatment
- From:
Chinese Journal of Clinical Oncology
2014;(20):1333-1336
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer has the highest morbidity and mortality rate among malignant tumors. Early diagnosis and effective treat-ment are the keys to improving the survival of lung cancer patients. A type of endogenous, highly conserved, non-coding small mole-cule RNA (i.e., miRNA) was found to play an important role in the occurrence and development of this disease. Research on this molec-ular marker miRNA for the diagnosis, treatment and prognosis of lung cancer has rapidly progressed. This paper reviews the research work on miRNA as a molecular marker in the early diagnosis, treatment efficacy, and prognosis of lung cancer and explores some ques-tions related to this disease.
