The utility of apparent diffusion coefficient in differential diagnosis of common pediatric cerebellar tumors
10.3969/j.issn.1002-1671.2015.06.029
- VernacularTitle:ADC 值在儿童常见小脑肿瘤鉴别诊断中的应用
- Author:
Chunxiao BU
;
Yong ZHANG
;
Jingliang CHENG
;
Yanliang LI
- Publication Type:Journal Article
- Keywords:
apparent diffusion coefficient;
medulloblastoma;
ependymomas;
astrocytomas
- From:
Journal of Practical Radiology
2015;(6):998-1001
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the assessment value of diffusion-weighted magnetic resonance imaging (DWI)and apparent diffusion coefficient (ADC)in the differential diagnosis of common cerebellar tumors of children.Methods 45 patients with cerebel-lar tumors were retrospectively analyzed,including 23 medulloblastomas,14 astrocytomas,and 8 ependymomas .The ADCmin of parenchyma of different tumors were measured and Receiver operating characteristic (ROC)curve were delineated.The optimum ADC value for differential diagnosis of common cerebellar tumors of children was analyzed and determined.Results The mean ADC-min of medulloblastoma (0.497 ± 0.023 )× 10 -3 mm2/s was lowest,the mean ADCmin of astrocytoma (1.572 ± 0.145 )× 10 -3 mm2/s was highest,while that of ependymoma was (0.784 ± 0.037 )× 10 -3 mm2/s.The optimum ADC to distinguish ependymomas from medulloblastomas was 0.61 1 × 10 -3 mm2/s (100% sensitivity and 95.7% specificity).The optimum ADC to distinguish low-grade astrocytomas from ependymomas was 1.064×10 -3 mm2/s (92.9% sensitivity and 100% specificity).Conclu-sion ADC is very helpful with differential diagnosis of common cerebellar tumors of children.
