Recent progress in pharmacogenomics of repaglinide
10.3760/cma.j.issn.1000-6699.2015.02.023
- VernacularTitle:瑞格列奈药物基因组学研究进展
- Author:
Miao CHEN
;
Cheng HU
;
Weiping JIA
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Phamacogenomics;
Repaglinide
- From:
Chinese Journal of Endocrinology and Metabolism
2015;(2):185-187
- CountryChina
- Language:Chinese
-
Abstract:
Repaglinide is one of the most commonly used oral antidiabetic drugs. It can lower postprandial plasma glucose by means of initiating early-phase insulin release through closing the ATP-dependent potassium channels. Phamacogenomics is a branch of genetics which deals with the genetic variability in individual responses to drugs and drug metabolism. The progress of phamacogenomic study on repaglinide is summarized in this article.
