Research of prognostic indicators in T1a renal cell carcinoma
10.3969/j.issn.1671-8348.2014.31.036
- VernacularTitle:T1a 期肾细胞癌预后判断指标研究
- Author:
Hao LIN
- Publication Type:Journal Article
- Keywords:
T1a renal cell carcinoma;
Fuhrman nuclear grading;
prognosis;
recurrence
- From:
Chongqing Medicine
2014;(31):4227-4229
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study prognostic indicators in T1a renal cell carcinoma(RCC) from perspective of pathology .Methods Three hundred and thirty - eight patients with single sex renal cell carcinoma were collected from January 1996 to January 2013 in our hospital ,we retrospectively analyzed their clinical pathological features and the relationship between the disease progression , and explored the factors that affect the recurrence and distant metastasis .Results 11 cases(3 .3% ) patients were identified as a tumor recurrence ,9 of them had a clear metastatic lesions .Multi factor analysis results showed that the high tumor grade (level 3 and level 4) was an independent risk factor for tumor recurrence (hazard the wire :13 .0 ,95% CI :3 .90 - 43 .00 ,P < 0 .01) ;while age ,sex ,tumor size ,histological manifestations ,infringement of microcirculation and the operation factors such as boundary condi‐tion had no obvious correlation with tumor recurrence .Five years relapse free survival in patients with tumor grade high was 67 .8% ,compared with 96 .8% in the lower graded .Conclusion Fuhrman nuclear grading is a reliability index to judge the progno‐sis of T1a renal cell carcinoma postoperative recurrence and metastasis ,and higher class T1a phase need strengthening postoperative follow up and monitoring .
