Review and prospects on research and application of hematopoietic stem cell transplantation

VernacularTitle:造血干细胞移植研究和应用的回顾与展望
Author: Ding TIAN
Publication Type:Journal Article
Keywords: Hematopoietic stem cell transplantation; HLA-matched sibling donor transplantation; Cord Blood Stem Cell Transplantation; Unrelative donor transplantation; HLA haploidentical transplantation; Donor safety
From: Journal of Leukemia & Lymphoma 2013;22(6):327-330
CountryChina
Language:Chinese
Abstract: The outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been improved over past 50 years due to the advances in HLA matching and increasing sources of HSC donors,such as developments and progressions of HLA-matched sibling donor transplantation (MSDT),umbilical cord transplantation (UCBT/CBT),unrelative donor transplantation (URDT),and HLA haploidentical transplantation (haplo-SCT).To review and discuss progressions in field of allo-HSCT,we studied relative advances reports of Education Program Book,54th-ASH,2012.Howeover,the outcomes of allo-HSCT can be quite different according to different diseases,disease phase or patient age.Furthermore,according to our local experiences,we emphasize again significance of HSCT donor safety.