Clinical efficacy of cattle encephalon glycoside and ignotin injection with salviae miltiorrhizae and ligustrazine hydrochloride injection for acute cerebral infarction
- VernacularTitle:脑苷肌肽联合丹参川芎嗪注射液对急性脑梗死的临床疗效研究
- Author:
Qingguo LIN
;
Yanyan LI
- Publication Type:Journal Article
- Keywords:
cattle encephalon glycoside and ignotin;
salvia ligustrazine injection;
acute cerebral infarction
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;37(7):111-113
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of cattle encephalon glycoside and ignotin with salviae miltiorrhizae and ligustrazine hydrochloride injection for acute cerebral infarction.Methods 50 patients with acute cerebral infarction from July 2012 to October 2013 admitted in our hospital were randomly divided into observation group and control group.Observation group had 25 patients,they were treated with cattle encephalon glycoside and ignotin with salviae miltiorrhizae and ligustrazine hydrochloride injection.Control group had 25 patients,they were treated with only salviae miltiorrhizae and ligustrazine hydrochloride injection.After two groups'treatment,the clinical efficacy,indicators of hemorheology (include whole blood viscosity,platelet aggregation and plasma viscosity),neurological deficiency score and activity of daily life were observed and compared.Results There was no significant difference in the clinical data between two group.After treatment,the total efficiency rate in observation group and control group were 92.00% and 60.00%,separately,the difference between two group was significant (u=2.4129,P=0.0158);the whole blood viscosity (high cut, low cut)of observation group were shorter than control group(P<0.05 );platelet aggregation of observation group were shorter than control group(t=0.5632,P=0.5759);plasma viscosity of observation group were shorter than control group(t=3.7682,P=0.0004);the neurological deficiency score and activity of daily life of observation group were shorter than control group(t =3.7682,P=0.0004).Conclusion The clinical efficacy of cattle encephalon glycoside and ignotin with salviae miltiorrhizae and ligustrazine hydrochloride injection for acute cerebral infarction is well.
