The application of MR imaging in differentiating benign and malignant lymph node and assessing therapeutic effect
10.3969/j.issn.1002-1671.2014.10.027
- VernacularTitle:MR I在良恶性淋巴结病变诊断及疗效评估中的应用
- Author:
Caixian HAO
;
Jun LIU
;
Jin ZHONG
;
Liang XU
;
Xiuling ZHANG
;
Yulin ZHANG
;
Changqing ZONG
;
Hui QIAO
- Publication Type:Journal Article
- Keywords:
magnetic resonance imaging;
diffusion weighted imaging with background suppression;
lymph node
- From:
Journal of Practical Radiology
2014;(10):1706-1709
- CountryChina
- Language:Chinese
-
Abstract:
Objective To approach the application value of diffusion weighted imaging with background suppression (DWIBS) combined with routine MR sequence in differentiating benign and malignant lymph nodes,and assessing therapeutic effect of lympho-genic tumors.Methods 48 patients with cervical lymph node enlargement who were confirmed by pathology and follow up under-went DWIBS and routine MRI examination,malignant lymph nodes were 83,benign lymph nodes were 79.16 patients with malig-nant lymph nodes were rechecked after radiotherapy and chemotherapy,Apparent diffusion coefficient (ADC)values of the solid part for lymph nodes were compared.Results More lymph nodes can be detected in DWIBS than conventional sequence.ADC values of the solid part for malignant lymph node(0.898±0.111)×10-3 mm2/s were lower than that of benign lymph node(1.043±0.106)× 10-3 mm2/s,there was significant difference between them (P<0.05).ADC values of all malignant lymph nodes after treatment (1.205±0.121)×10-3 mm2/s were significantly higher than that of pretherapy (0.883±0.090)×10-3 mm2/s (P<0.05).Conclu-sion DWIBS could more sensitively detect lymph node than conventional MR sequence.ADC value could provide some reference values for differentiating benign and malignant lymph nodes and assessing therapeutic effect.
