Clinical Distribution and the Detection of Multiple Drug-Resistant Acinetobacter Baumannii Efflux Pump Genotypes
10.3969/j.issn.0253-9896.2014.11.014
- VernacularTitle:多重耐药鲍曼不动杆菌临床分布及外排泵基因的检测
- Author:
Jingna SUN
;
Qingsong LIU
;
Yan WU
;
Guoxin WANG
;
Zeshi LIU
;
Zheng ZHANG
- Publication Type:Journal Article
- Keywords:
acinetobacter baumannii;
microbial sensitivity tests;
multiple drug resistant;
efflux pump gene
- From:
Tianjin Medical Journal
2014;(11):1103-1105
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical distribution and detection of the efflux pump gene in multiple drug-re?sistant acinetobacter baumannii. Methods The clinical distribution of 96 strains of multiple drug-resistant acinetobacter baumannii was analyzed. K-B method was used to detect 96 strains of multi resistant bauman resisted to 15 kinds of antibiot?ics. PCR amplification was used to detect the efflux pump gene. Results Ninety-six strains of multiple drug-resistant aci?netobacter baumannii mainly distributed in intensive care unit (ICU, 54.2%) and respiratory department (18.8%). The drug resistance rates to quinolone, cephalosporins, amino glucoside, tetracycline were above 70%. The 52 strains of multiple drug-resistant acinetobacter baumannii detected in ICU included 18 strains of adeB (34.62%), 16 strains of adeR (30.77%), 18 strains of adeS (34.62%), 18 strains of adeJ (34.62%), 0 strain of adeE and18 strains of adeM (34.62%). The18 strains of multiple drug-resistant acinetobacter baumannii detected in respiratory department included 9 strains of adeB, 8 strains of adeR, 8 strains of adeS, 8 strains of adeJ, 0 strain of adeE and 8 strains of adeM. Conclusion Efflux pump genes are impor?tant factors for multiple drug-resistant acinetobacter baumannii distributed in ICU and respiratory department.
