Application of liposome in cancer therapy and tracer study
10.3969/j.issn.1000-8179.20140740
- VernacularTitle:脂质体在肿瘤治疗和示踪研究中的新进展
- Author:
Jie DING
;
Lijiang HU
;
Xing KANG
;
Ke CAO
;
Wenxian GUAN
- Publication Type:Journal Article
- Keywords:
liposome;
polyethylene glycol;
targeting;
tracing;
magnetic resonance imaging
- From:
Chinese Journal of Clinical Oncology
2014;(21):1403-1407
- CountryChina
- Language:Chinese
-
Abstract:
Liposome is an artificially prepared spherical vesicle that has a phospholipid bilayer. Given that the basic structure of its biological membrane is also a lipid bilayer membrane, liposome shares similar structures with body cells Therefore, liposome has good biocompatibility and advantages such as biodegradability, low immunogenicity, and subtle toxicity. Liposome has been widely ap-plied as an effective drug carrier. Studies on liposome-encapsulated fluorescent dye on tumor tracing have been reported in recent years. Liposome can become a more advantageous transport carrier with continuous development of surface modification materials and prepa-ration methods. The long cycle, targeted liposome-encapsulated drugs, and fluorescent dye have become the focus of interest for several researchers. This article mainly discusses the application and progress of long cycle and targeted liposome in cancer research.
