Effects and prognosis of aspirin combination with atorvastatin in the treatment of patients with cerebral in-farction
10.3760/cma.j.issn.1008-6706.2014.21.024
- VernacularTitle:阿司匹林联合阿托伐他汀钙治疗急性脑梗死的效果及预后分析
- Author:
Shaohong WANG
;
Shaobo WANG
- Publication Type:Journal Article
- Keywords:
Brain Infarction;
Aspirin;
Atorvastatin calcium;
Prognosis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(21):3262-3264
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects and prognosis of aspirin combined with atorvastatin calcium for the treatment of acute cerebral infarction.Methods According to the digital table,80 patients with acute cerebral infarction were selected and randomly divided into the control group and observation group,each group 40 cases.The patients in control group were given aspirin enteric-coated metformin hydrochloride 100mg/d treatment,while the ob-servation group was treated in the control group taking on the basis of atorvastatin calcium 20mg/d.After the continu-ous treatment of 4 weeks,the curative effects were compared between the two groups,and the different hs-CRP levels in the body of the prognosis of patients were analyzed.Results The total effective rate of the observation group was 95%,which was higher than 75%of the control group(χ2 =3.98,P<0.05);The total curative effect of patients with abnormal hs-CRP levels in the control group was 65%,while that in the observation group was 92%,there was statis-tically significant diference between the two groups(χ2 =4.21,P<0.05);The total curative effect of patients with normal hs-CRP levels in the control group was 94%,while that in the observation group was 100%,there was no sta-tistically significant difference between the two groups(χ2 =1.32,P>0.05).Conclusion Aspirin combination with atorvastatin calcium for the treatment of acute cerebral infarction exactly can well improve the prognosis,which is wor-thy of clinical popularization and application.
