Significance of detection of Hcy,hs-CRP and cTnT in patients with coronary heart diseases
10.3969/j.issn.1673-4130.2015.01.003
- VernacularTitle:冠心病患者同型半胱氨酸、超敏C反应蛋白和心肌肌钙蛋白T检测的临床意义
- Author:
Hui LI
;
Xingning WANG
;
Dong ZHAO
- Publication Type:Journal Article
- Keywords:
coronary heart diseases;
homocysteine;
high sensitivity C-reactive protein;
cardiac treponin T
- From:
International Journal of Laboratory Medicine
2015;(1):8-9
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the significance of plasma homocysteine(Hcy),high sensitivity C-reactive protein(hs-CRP)and cardiac treponin T(cTnT)changes in the patients with coronary heart diseases(CHD).Methods From August 2012 to November 2013,240 patients with CHD in our hospital were collected as the CHD group and 250 individuals of healthy physical examination served as the control group.Serum Hcy,hs-CRP and cTnT were detected by using the enzymatic cycle assay,immune scatter turbi-dimetry and electrochemiluminescence assay respectively.The data were statistically analyzed by the SPSS software.Results The serum levels of Hcy,hs-CRP and cTnT in the CHD group were (24.89±17.78)μmol/L,(17.43±35.89)mg/L and (0.76±2.36) ng/mL respectively,which were significantly higher than those in the control group(P <0.001).Moreover,the positive rate of Hcy in the CHD group was the highest (81 .25%),followed by hs-CRP(64.58%)and cTnT (58.75%).Conclusion Hcy,hs-CRP and cTnT played important roles in the development and progression of CHD,so reducing Hcy level may be an important pathway for preventing and treating CHD.
