Measurement and clinical significance of D-dimer during perioperative period in advanced age patients with hip fracture

VernacularTitle:高龄髋部骨折患者围术期 D-二聚体的测定及临床意义
Author: Yan LU ; Pan CAI ; Mingrong TANG ; Jun DAI ; Yan WANG
Publication Type:Journal Article
Keywords: D-dimer; advanced age; hip fracture; lower limbs deep vein thrombosis; perioperation period
From: International Journal of Laboratory Medicine 2015;(1):25-26
CountryChina
Language:Chinese
Abstract: Objective To investigate the change and clinical significance of blood D-dimer level during perioperative period in ad-vanced age hip fracture.Methods The blood D-dimer level in 60 patients aged over 80 years old with hip fracture was detected be-fore operation and after operation,which including at admission(T1 ),immediately preoperation(T2 ),immediately postoperation (T3 )and on postoperative 1 d (T4 ).Results The positive rates of D-dimer at T1 ,T2 ,T3 and T4 were 6.67%,16.45%,41.67%and 80.00% respectively;there were statistically significant differences between T3 ,T4 and T1 ,T2 ,between T3 and T4 (P <0.05);there was no statistically significant difference between T1 and T2 (P >0.05).Conclusion The level of D-dimer in advanced age hip fracture has significant change before and after operation.The change of the D-dimer positive rate is an effective index for preven-ting lower limbs deep venous thrombosis and has the important clinical significance to dynamically monitor the D-dimer level during perioperative period in advanced age hip fracture.