Drug resistance and distribution of clinical Providencia stuartii isolates
10.3760/cma.j.issn.1008-6706.2014.22.010
- VernacularTitle:斯氏普罗威登菌医院感染状况及耐药性分析
- Author:
Jiayang QIU
;
Jiachang LIU
;
Qiuming QU
- Publication Type:Journal Article
- Keywords:
Providencia stuartii;
Drug sensitivity test
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(22):3383-3385
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the distribution and drug resistance of clinical Providencia stuartii isolates and provide the basis data for clinical therapy.Methods A data analysis for the specimen source,the distribution of departments with infection and the antibiotic susceptibility results to 76 isolates was conducted in retrospectively. Results Among 76 strains were mainly from sputum (71.1%),wound secretions (10.5%) and blood (6.6%);the proportion of these strains from ICU was 40.8%,from respiratory department was 9.2%and from general surgery was 7.9%;The bacteria's drug resistance was more serious,multi drug resistant (MDR) strains accounted for 65.8%,pan drug resistant ( PDR) strains accounted for 26.3%,the mortality of patients with PDR strains infection was 45.0%,which was higher than 5.8%of no PDR strains infection.A low resistance rate of antibiotics were imipenem,fluoro-quinolones andamikacin,et al,and the rate of imipenem resistant was lowest(31.5%).Conclusion The multidrug resistance phenomenon of Providencia stuartii is serious, the first choice for the treatment is imipenem, the second choice was fluoroquinolones or amino glycopeptides antibiotics,the hospital infection caused by the bacterium infection in monitoring should be strengthened.