Clinical application of combined detection of CEA,CA125 and LDH in benign and malignant hydrothorax and ascites identification
10.3969/j.issn.1673-4130.2015.01.039
- VernacularTitle:CEA、CA125、LDH 联合检测对良恶性胸、腹腔积液鉴别的临床应用
- Author:
Xiang GAO
- Publication Type:Journal Article
- Keywords:
hydrothorax and ascites;
carcinoembryonic antigen;
carbohydrate antigen 125;
lactate dehydrogenase
- From:
International Journal of Laboratory Medicine
2015;(1):91-92
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical application value of the determination of carcinoembryonic antigen (CEA),car-bohydrate antigen 125 (CA125)and lactate dehydrogenase (LDH)in the differential diagnosis of malignant hydrothorax and asci-tes.Methods The Beckmancoulter ACCESS2 automatic micro particle chemiluminescence immunoassay analyzer was adopted to determine the CEA and CA125 levels in hydrothorax and ascites,and the Roche C501 automatic biochemical analyzer was used to determine the LDH level in hydrothorax and ascites.The clinical application value of these three indicators in the evaluation of be-nign and malignant hydrothorax and ascites was evaluated.Results The differences in the expression levels of CEA,CA125 and LDH between benign and malignant hydrothorax and ascites had statistical significance (P <0.01 );the positive rate of CEA, CA125 and LDH in malignant hydrothorax and ascites were 84.21%,92.98%,75.44%.Conclusion The combined detection of CEA,CA125 and LDH has an important value in differential diagnosis of benign and malignant hydrothorax and ascites.
