Malignant Peripheral Nerve Sheath Tumor in Descending Colon: A Case Report.
- Author:
Young S PARK
1
;
Sung Jing LIM
;
Woo Ho KIM
;
Eui Keun HAM
Author Information
1. Department of Pathology, Seoul National University College of Medicine, Seoul, Korea. WoohoKim@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Nerve Sheath Tumors;
Colonic Neoplasms
- MeSH:
Adult;
Colon;
Colon, Descending*;
Colonic Neoplasms;
Humans;
Keratins;
Nerve Sheath Neoplasms;
Neurofibromatoses;
Parasites;
Peripheral Nerves*;
S100 Proteins
- From:Korean Journal of Pathology
2002;36(3):179-183
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a unique case of malignant peripheral nerve sheath tumor (MPNST) of colon, not associated with neurofibromatosis or parasite infection. The tumor presented as an encircling mass in descending colon causing obstruction with nuberous metastatic lesions in a 43-year-old man. The tumor was largely composed of spindle cells which showed strong positivity for vimemtin, S-100 protein and Leu-7. The tumor often exhibited epithelioid feature where tumor cells were weakly positive for cytokeratin.
