Investigation of the serum levels of CysC and NT-proBNP in the patients with hypertension
10.3969/j.issn.1673-4130.2014.21.009
- VernacularTitle:高血压患者血清胱抑素C和N端脑钠肽前体水平研究
- Author:
Gangwen PENG
;
Weiqiang LI
- Publication Type:Journal Article
- Keywords:
hypertension;
cystatin C;
N-terminal pro-brain natriuretic peptid
- From:
International Journal of Laboratory Medicine
2014;(21):2885-2886
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of serum levels of CysC and NT-proBNP in patients with hypertension .Meth-ods 89 patients with hypertension were selected and divided into five subgroups:Group A (n= 20) with simple hypertension;Group B(n=18) with hypertension and left ventricular hypertrophy ;Group C(n=15) with hypertension and heart failure;Group D(n=17) with hypertension and early renal damage;Group D(n=19) with hypertension and coronary heart disease .20 healthy in-dividuals were selected as control group .The serum levels of CysC and NT-proBNP were measured in all the groups .Results The serum levels of CysC in group B ,C and D were higher than control group (P<0 .05) ,and serum CysC level in group E was lower than control group(P<0 .05) .The serum level of NT-proBNP in group D was higher than control group(P<0 .05) ,and the serum NT-proBNP levels in group B ,C and E were significantly higher than control group (P<0 .01) .Conclusion The detection of CysC and NT-proBNP in patients with hypertension is helpful for understanding the progression of the disease and the occurrence of amalgamative diseases ,and it provides positive proof for clinical treatment .
