Results analysis of irregular antibodies screening and identification of the specificity
10.3969/j.issn.1673-4130.2014.21.011
- VernacularTitle:不规则抗体筛查及特异性鉴定结果分析
- Author:
Xiaoling WANG
;
Lijun MEI
- Publication Type:Journal Article
- Keywords:
irregular antibody;
specificity;
blood transfusion;
transfusion reaction
- From:
International Journal of Laboratory Medicine
2014;(21):2889-2890
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the distribution of irregular antibodies of red blood cells and its clinical significance .Methods Micro-column gel anti-globulin technique was used to screen and identify the irregular antibodies in 6 352 patients .Results In 6 352 patients ,there were 62 cases(27 males ,35 females)having positive results in irregular antibody detection ,and the positive rate was 0 .97% .There were 54 cases having transfusion history and/or pregnancy history ,including 43 cases of irregular antibodies of Rh system(containing 34 cases of anti-E antibody) ,7 cases of MNSS system ,2 cases of Lewis system ,2 cases of Kidd system ,2 cases of P system ,1 cases of Diego system ,and 5 cases with non-specificity .All of the patients whose irregular antibodies of Rh blood group system were positive had transfusion history and/or pregnancy history .Conclusion Most of the patients with irregular anti-body positive are females ,who mostly have transfusion history and/or pregnancy history ,and the irregular antibodies of Rh system are the most common .