Research progress of subchondral bone in osteoarthritis
- VernacularTitle:软骨下骨在骨性关节炎中的研究进展
- Author:
Hua ZHU
;
Faming TIAN
;
Liu ZHANG
- Publication Type:Journal Article
- Keywords:
Osteoarthritis;
Subchondral bone;
Bone remodeling
- From:
Journal of Medical Postgraduates
2014;(10):1095-1098
- CountryChina
- Language:Chinese
-
Abstract:
Osteoarthritis ( OA) is a chronic joint disease characterized by degeneration of articular cartilage and changes of subchondral bone play an important role in the occurrence and development of OA .Recent studies have found that change in the struc-ture and mechanical properties of subchondral bone is one of the main pathological processes in OA .To confirm the role of subchondral bone in OA process can provide not only more details about the pathogenesis of OA , but also new targets for treatment .Early diagnosis and treatment of OA may be possible by detecting radiographic and genomics of subchondral bone .We review subchondral bone chan-ges andits role in OA process in aspects of biomechanics , biology, radiological and genomics .
