Advance on mechanisms of metformin′s anti-lung-cancer activity
- VernacularTitle:二甲双胍抗肺癌机制的研究进展
- Author:
Yongyuan JIANG
;
Hu LUO
;
Xiangdong ZHOU
- Publication Type:Journal Article
- Keywords:
Metformin;
Lung cancer;
Mechanism
- From:
Journal of Medical Postgraduates
2014;(10):1114-1117
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes and lung cancer are common diseases worldwide , which have a serious impact on human health .Recently epidemiologic research has found that diabetes , which may enhance the incidence of lung cancer , is one of the risk factors of lung canc-er.The metformin, a first-line drug for treatment of type 2 diabetes, can decrease the incidence of lung cancer and may have an anti-lung-cancer bioactivity ,but its mechanisms are unclear .To make a further study of the mechanisms is expected to reduce the morbidity and is possible to help us find a new therapeutic target .The aim of this article is to review the potential mechanism of the metformin′s anti-lung-cancer activity .
