Research progress of mechanism of tumor radioresistance
10.3760/cma.j.issn.1673-422X.2014.10.009
- VernacularTitle:肿瘤放疗抵抗机制研究进展
- Author:
Shan LIU
;
Yongxin JIANG
;
Wei XIONG
;
Fenglian FU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Therapy;
Radiotherapy
- From:
Journal of International Oncology
2014;41(10):747-749
- CountryChina
- Language:Chinese
-
Abstract:
Tumor radioresistance is the leading cause of clinical radiotherapy failure and disease progression.Researches show that the occurrence of radioresistance is related to the cell cycle arrest,relevant gene change,tumor microenvironment change,autophagy,tumor stem cells and other factors.Studying the mechanism of radioresistance and looking for an effective method to avoid it is the key to improve the effect of radiotherapy,which can provide the probability of the prognosis of radiosensitivity.
