Effects of Acupuncture Therapy on Triglyceride of Quadriceps Femoris in High Fat Diet Feeding-induced Insulin Resistance Rats
10.3969/j.issn.1005-5304.2014.11.021
- VernacularTitle:“标本配穴”针刺对高脂饮食所致胰岛素抵抗大鼠股四头肌中三酰甘油的影响
- Author:
Liu YANG
;
Qiang LI
;
Fen XU
;
Fei MIN
;
Song WU
;
Jianmin LIU
;
Hongtu TANG
;
Zebin CHEN
;
Fengxia LIANG
- Publication Type:Journal Article
- Keywords:
adjunct acupuncture points;
acupuncture;
insulin resistance;
TG;
skeletal muscle
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(11):69-71
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of acupuncture therapy on triglyceride (TG) content of quadriceps femoris in the high fat diet feeding-induced insulin resistance rats; To discuss acupuncture mechanisms to improve the insulin sensitivity. Methods Thirty-two Wistar rats at the age of eight weeks were randomly divided into normal group, model group, electro-acupuncture group, and sham electro-acupuncture group. The normal group was given basic diet, and model group, electro-acupuncture group and sham electro-acupuncture group were given high fat diet for 8 weeks, after which, the model of insulin resistance was successfully obtained. Electro-acupuncture group was given acupuncture therapy with “Guanyuan (GV4)”, “Zhognwan (GV12)”, “Zusanli (ST36)”, and “Fenglong (ST40)” for 8 weeks. Sham electro-acupuncture group was given stimulation at non-acupuncture points which were not on the meridians and near the acupoints but not at the area of the acupoints. In addition, food intake and body weight of each group were recorded, blood glucose was tested, TG content of quadriceps femoris was measured by enzymatic method after the treatment. Results The weight of the rats and TG levels of quadriceps femoris in electro-acupuncture group and sham electro-acupuncture group were significantly lower than those in model group, with significant statistical difference (P<0.05), especially in electro-acupuncture group. Conclusion Acupuncture therapy could improve insulin sensitivity to prevent and its related diseases.
