Randomized controlled study on mechanical ventilation with bronchoalveolar lavage therapy for COPD combined with respiratory failure
10.3969/j.issn.1006-5725.2014.18.018
- VernacularTitle:机械通气联合支气管肺泡灌洗治疗 COPD 合并呼吸衰竭随机对照研究
- Author:
Rong ZHU
;
Yongqing HONG
;
Zili MENG
;
Wei CHEN
- Publication Type:Journal Article
- Keywords:
Mechanical ventilation;
Bronchoalveolar lavage;
Chronic obstructive pulmonary disease;
Respiratory failure
- From:
The Journal of Practical Medicine
2014;(18):2919-2921
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of continuous invasive mechanical ventilation combined with BAL on COPD patients with respiratory failure. Methods Sixty COPD patients with respiratory failure were divided into BAL and control group randomly. Control group were treated with sputum suction tube to aspire sputum and BAL group treated with BAL. The changes in the indicators were observed. Results The SpO2, airway peak inspiratory pressure and blood gas analysis were improved significantly compared with the control group (P < 0.01). The number of peripheral blood leucocytes and the level of CRP in BAL group were lower than those in control group at the seventh day (P < 0.01). The duration of invasive mechanical ventilation and hospital stay in BAL group was shorter than that in control group (P < 0.01) and there was no severe complication in both groups. Conclusion BALwith continuous mechanical ventilation support are safe and effective and shorten hospitalization time and improve the prognosis of COPD patients with respiratory failure.
