The value of detection of serum myocardial enzyme spectrum and cardiac troponin I in neonatal hypoxic ischemic encephalopathy
10.3969/j.issn.1673-4130.2014.19.016
- VernacularTitle:新生儿缺氧缺血性脑病患者血清心肌酶谱及cT nI水平变化及临床意义
- Author:
Fumingjun LIU
;
Zhenhua QIU
;
Junsheng XU
;
Zecheng CHEN
- Publication Type:Journal Article
- Keywords:
myocardial enzyme spectrum;
cardiac troponin I;
neonatal hypoxic ischemic encephalopathy
- From:
International Journal of Laboratory Medicine
2014;(19):2611-2612
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the value of analysis of serum myocardial enzyme spectrum and cardiac troponin I(cTnI) in neonatal hypoxic ischemic encephalopathy(HIE) .Methods Serum level of myocardial enzyme spectrum in each people was deter-mined with Hitachi 7602 ,Serum levels of cTnI was determined by chemoluminescence method .Serum levels of myocardial enzyme spectrum and cTnI were collect from 65 neonates with HIE(HIE group) and 68 cases of helthy volunteers(control group) .Results The levels of glutamic oxalacetic transaminase(AST) ,creatine kinase(CK) ,creatine kinase MB isoenzyme(CK-MB) ,lactic dehy-drogenase(LDH) and alpha-hydroxybutyric dehydrogenase(HBDH) in HIE group were(98 .9 ± 9 .6)U/L ,(385 .4 ± 15 .5)U/L , (89 .3 ± 9 .6)U/L ,(300 .8 ± 19 .8)U/L ,(399 .1 ± 17 .9)U/L ,which were higher than those in control group(P<0 .05) .The level of cTnI was(1 .4 ± 0 .4)ng/mL in HIE group ,which was higher than that in control group(P<0 .05) .CK-MB sensitivity was 88 .6% , cTnI speciality rate was 86 .3% .Conclusion The assay of myocardial enzyme spectrum and cTnI is significant in diagnosis of neo-natal HIE .
