The clinical value of HbA1c,CRP,IL-6 and IMA in patients with type 2 diabetes nephropathy
10.3969/j.issn.1673-4130.2014.19.019
- VernacularTitle:HbA1c、CRP、IL-6和IMA对糖尿病肾病早期诊断的价值
- Author:
Xiaohua HUANG
;
Chaolin HUANG
;
Yanbin ZHENG
- Publication Type:Journal Article
- Keywords:
diabetic nephropathy;
C-reactive protein;
interleukin-6;
ischemia modified albumin
- From:
International Journal of Laboratory Medicine
2014;(19):2618-2619
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of glycosylated hemoglobin A1(HbA1c) ,C-reactive protein(CRP) ,interleu-kin-6(IL-6) and ischemia modified albumin(IMA) in patients with type 2 diabetes nephropathy .Methods 64 patients with type 2 diabetes mellitus were divided into simple diabetic mellitus group(34 patients) and diabetic nephropathy group(30 patients) .In ad-dition ,40 healthy subjects were chosen as control group .The levels of HbA1c ,CRP ,IL-6 and IMA were detected .Results The lev-els of HbA1c ,CRP ,IL-6 and IMA in simple diabetic mellitus group were all significantly higher than those in control group(P<0 .05) .The levels of HbA1c ,CRP ,IL-6 and IMA in diabetic nephropathy group were all significantly higher than those in simple di-abetic mellitus group(P<0 .05) .There were a positive correlations between the HbA1c level and the levels of CRP ,IL-6 ,IMA(P<0 .05) .The positive rate of combined detection of HbA1c ,CRP ,IL-6 and IMA was significantly higher than separate index detection (P<0 .05) .Conclusion The combined detection of HbA1c ,CRP ,IL-6 and IMA may be beneficial to the early diagnosis of diabetic nephropathy ,which will delay the progress of diabetic nephropathy .
