The application of the joint detection of mALB,α1-M and NAG in the diabetes and hypertension patients with early injury of kidney
10.3969/j.issn.1673-4130.2014.19.020
- VernacularTitle:尿液中mALB、α1-M 和 NAG联合检测在诊断糖尿病和高血压患者肾脏早期损伤中的应用
- Author:
Ning GAO
;
Miaoxian LI
;
Nan XU
;
Ruihua YANG
;
Lihua ZHAO
;
Xiangling WANG
- Publication Type:Journal Article
- Keywords:
microalbumin;
α1-microglolin;
N-acety-β-D-glucosaminidase;
the early injury of kidney
- From:
International Journal of Laboratory Medicine
2014;(19):2620-2621
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnosis value of joint detection of microalbumin(mALB) ,α1-Microglolin(α1-M ) and N-acety-β-D-glucosaminidase(NAG) in the diabetes and hypertension patients with early injury of kidney .Methods Sample were col-lected from July 2013 to January 2014 ,including 63 diabetic cases(diabetic group) ,58 patients with hypertension(hypertension group) and 64 health controls(control group) ,then the levels of urinary mALB ,α1-M were detected by immunoturbidimetry ,urina-ry NAG activity was assessed by endpoint colorimetric assay .Results The levels of urinary mALB ,α1-M and NAG in diabetic group and hypertension group were higher than those in control group(P<0 .05) .The positive rates of three indices single detected were less than 50 .0% ,the positive rates of any two indices joint detected were more than 50 .0% ,the positive rate of three indices joint detected was more than 70 .0% .Conclusion The method of urinary mALB ,α1-M and NAG joint detected is sensitive and reli-able for diagnosing of the early injury of kidney .
