Preparation and Efficacy Evaluation of the Placebos of Sicao Tongmai Capsules
- VernacularTitle:中药制剂四草通脉胶囊安慰剂制备方法及效果评价
- Author:
Guanqin JIN
;
Linghong XIA
;
Li SUN
- Publication Type:Journal Article
- Keywords:
TCM placebo;
Sicao Tongmai capsules;
Preparation methods;
Clinical trials on TCM;
Evaluation
- From:
China Pharmacist
2014;(12):2013-2015
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To prepare the placebos of Sicao Tongmai capsules to provide the reference for the placebo preparation in clinical trials of traditional Chinese medicines. Methods: Taking the placebo preparation of Sicao Tongmai capsules as the example, the appearance, color and smell of the placebo were assessed by the scoring method and an electronic nose. Results:The appearance, color and taste of the placebo were in line with those of the drug powder, while there was difference in smell. The simulated clinical ex-periments showed that the placebo was difficult to be unblinded. Conclusion:The placebo can be used in TCM clinical trials, howev-er, the production technology should be further improved and modified.
