Clinical Efficacy of Recombinant Human Interferon α-2b Gels Combined with Ulcer Powders for External Use in the Treatment of Cervicitis with Human Papillomavirus Infection
- VernacularTitle:重组人干扰素α-2b凝胶联合外用溃疡散治疗人乳头瘤病毒感染宫颈炎疗效观察
- Author:
Yangqin HUANG
;
Aiduan PAN
;
Yong ZHU
- Publication Type:Journal Article
- Keywords:
Cervicitis;
HPV;
Recombinant interferon α-2b gels;
Ulcer powders for external use
- From:
China Pharmacist
2014;(12):2093-2095
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical efficacy of recombinant human interferon α-2b gels combined with ulcer powders for external use in the treatment of cervicitis patients with human papillomavirus infection. Methods: Totally 76 cases of cervicitis patients with human papillomavirus infection were randomly divided into the observation group and the control group. The observation group was treated by recombinant human interferonα-2b gels combined with ulcer powders for external use through vaginal administration, once every 2d on bedtime. The control group was treated only by ulcer powders for external use. After the 6-month treatment, the HPV negative conversion rate, clinical efficacy and adverse drug reactions in the two groups were detected. Results:After the treatment, the HPV negative conversion rate of the observation group was 83. 33%, which was higher than that of the control group (60. 00%, P <0. 001). The total effective rate of the observation group was 88. 89%, which was higher than that of the control group (82. 50%, P < 0. 05). Conclusion: The clinical efficacy of recombinant human interferon α-2b gels combined with ulcer powders for external use in the treatment of cervicitis patients with human papillomavirus infection is significant, which is worthy of wider application.
